Follow the Andes from Desert to Vineyard
One mountain range. Two countries. Three remarkably different landscapes.
The Andean Crossing follows the spine of the Andes through Chile and Argentina, beginning among the salt flats and high-altitude lagoons of the Atacama Desert before traveling south to the glaciers and granite peaks of Patagonia, then north again to the vineyards of Mendoza.
Across nine nights, stay at Awasi Atacama, Awasi Patagonia and Awasi Mendoza, with an overnight connection in Santiago between destinations. Each place reveals a different expression of the Andes, from desert terrain shaped by minerals and volcanic forces to ancient ice fields and rows of Malbec vines.
At every Awasi lodge, a private guide and dedicated 4WD allow the journey to remain personal. Days are shaped around your interests, pace and the conditions of the landscape rather than a fixed group schedule.
Your 9-Night Chile & Argentina Itinerary
Awasi Atacama — 3 Nights
Salt valleys, high-altitude lagoons and mineral-colored landscapes.
Santiago — 1 Night
An overnight connection in Chile’s capital before traveling south.
Awasi Patagonia — 3 Nights
Granite peaks, remote valleys and the glaciers of Torres del Paine.
Awasi Mendoza — 2 Nights
Malbec, vineyard roads and the foothills of the Andes.
Together, the nine-night South America itinerary offers a journey through some of Chile and Argentina’s most defining landscapes without rushing from one experience to the next.
First Stop — Atacama: Across the Desert
Begin in northern Chile.
Fly from Santiago to Calama, where your Awasi guide meets you for the private transfer to San Pedro de Atacama. The landscape changes almost immediately, opening into the immense plains, distant volcanoes and sculpted formations of one of the driest regions on Earth.
Your introduction begins at the Cordillera de la Sal, where wind and time have carved ancient seabed sediment into ridges whose salt content gives the landscape its pale, almost lunar appearance.
The following day, climb higher into the Andes toward the Lagunas Altiplánicas, a series of lagoons more than 4,000 metres above sea level where flamingos can be seen against an expansive mountain backdrop. Continue toward Piedras Rojas, where iron-rich rock formations create deep shades of red against the surrounding lagoon and desert.
Another day brings you to Cejar Lagoon, where high salt concentrations make floating effortless, before exploring the Ayllus surrounding San Pedro. These historic farming communities continue to draw water through irrigation canals with roots stretching back to pre-Inca times.
Before leaving Atacama, discover Rainbow Valley, where deposits of copper, iron and sulfur have painted bands of color across the hillsides.
Then return to Santiago for an overnight stay before continuing south.
Second Stop — Patagonia: Toward the Ice
From Santiago, fly to Puerto Natales, where a private transfer carries you into the wilderness surrounding Torres del Paine.
The scale changes here.
Open desert becomes forest and grassland. Salt lagoons become glacial lakes. Volcanoes on the horizon give way to granite peaks rising dramatically above the Patagonian steppe.
Begin at the Cuernos Lookout, facing the unmistakable Cuernos del Paine. Their pale granite and darker sedimentary caps create the distinctive two-tone silhouette that defines this corner of Patagonia.
The next day ventures farther from the familiar routes of Torres del Paine into Sierra Baguales, a remote valley where the landscape holds evidence of an ancient past. Marine fossils recall a time when the area rested beneath the sea, while feral horses roam the surrounding terrain.
Your final full day turns toward ice at the Grey Glacier Lookout. Part of the Southern Patagonian Ice Field, Grey Glacier descends toward Lago Grey, calving icebergs into the water below.
Three nights offer a concentrated Patagonia itinerary, but each day remains flexible. Weather can shift quickly here, and your private guide can adapt excursions according to conditions and your interests.
Final Stop — Mendoza: Among the Vineyards
The final chapter of the Andean Crossing slows the pace.
Travel north to Mendoza, where the Andes remain a constant presence but vineyards now stretch across the foreground.
Spend a full day discovering the wines of Luján de Cuyo, one of Argentina’s most celebrated wine regions and a historic home of Malbec. Private tastings introduce the character of the region before the evening turns toward another Argentine tradition with a tango performance.
The following day is experienced on two wheels.
Set out along Camino de las Carreras, following quiet backroads framed by vineyards, poplars and the acequias that have carried water through Mendoza for centuries. With the Andes rising beyond the vines, the ride offers a final perspective on the mountain range that has connected every stage of the journey.
From the driest desert to ancient ice and, finally, the vineyard: nine nights, with the Andes always within sight.
When to Take the Andean Crossing
The best time to visit Chile and Argentina for the complete Andean Crossing is largely determined by Patagonia.
Awasi Patagonia operates seasonally from October through April, while Awasi Atacama and Awasi Mendoza operate year-round. For travelers hoping to experience all three destinations in one journey, the route should therefore be planned within Patagonia’s operating season.
Within that window, each destination has its own rhythm. The Atacama’s dry climate makes desert exploration possible throughout the season, while Mendoza shifts from spring and summer greenery into its atmospheric late-summer and early-autumn harvest period.
Patagonia remains the most unpredictable. Sun, wind, rain and changing temperatures can arrive within the same day, making layers essential regardless of when you travel.
One Journey, Three Expressions of the Andes
The landscapes may change, but the way you travel remains distinctly Awasi.
At each lodge, your villa is paired with a private guide and dedicated 4WD vehicle. There are no fixed group departures to follow. Excursions can be adjusted according to the weather, arrival and departure times, activity level and whatever captures your curiosity along the way.
Santiago acts as the connection between each region, with one overnight stay included within the nine-night itinerary.
The result is a Chile and Argentina itinerary that feels expansive without being overwhelming: three destinations connected by a single mountain range, experienced entirely at your own pace.
Andean Crossing
What is included at each Awasi lodge?
At each destination, every villa is paired with a private guide and dedicated 4WD vehicle, alongside hosted meals and tailor-made excursions. Daily plans can be adjusted throughout the journey according to interests, weather and local conditions.
Are children welcome on the Andean Crossing?
All three Awasi lodges on this itinerary welcome guests aged 14 and older. Families traveling with younger children should contact the Awasi team directly to discuss available options.
Is the Andean Crossing suitable for a honeymoon?
Yes. Private villas, individually tailored excursions and personalised service make the journey particularly well suited to honeymoons, anniversaries and other milestone trips. The combination of adventure in Atacama and Patagonia with the slower pace of Mendoza also gives couples a varied experience within one journey.
Do I have to visit all three Awasi lodges?
No. This itinerary describes the complete nine-night Andean Crossing, but shorter journeys combining select Awasi destinations can also be arranged.
How many days do you need in Patagonia?
This itinerary includes three nights in Patagonia, allowing time to experience the Cuernos Lookout, Sierra Baguales and Grey Glacier Lookout. Guests who want to hike farther or explore more of Torres del Paine can extend the Patagonia portion of the journey.
What is the best time to visit Mendoza?
Mendoza can be visited year-round. February through April coincides with harvest season, bringing additional energy to the region’s vineyards and wineries. Because this itinerary focuses on wine tasting and cycling rather than harvest-specific activities, the Mendoza portion can be enjoyed throughout Awasi Patagonia’s October-to-April operating window.
What is the best time to visit the Atacama Desert?
The Atacama Desert can be visited throughout the year thanks to its dry climate. April through June and September through November typically offer particularly comfortable conditions and clear skies for exploring its high-altitude landscapes.
What is Patagonia weather like?
Patagonia is known for quickly changing conditions, including shifts between sunshine, wind, rain and cooler temperatures. Layers and adaptable outdoor clothing are recommended regardless of when you visit.
What is the best time to visit Patagonia?
Awasi Patagonia operates seasonally from October through April, making this the window for completing the full Andean Crossing itinerary. Conditions vary considerably throughout the season, and Patagonia weather can change rapidly within a single day.
How many nights is the Andean Crossing itinerary?
The itinerary includes nine nights total: three nights at Awasi Atacama, one connecting night in Santiago, three nights at Awasi Patagonia and two nights at Awasi Mendoza.
What is the Andean Crossing itinerary?
The Andean Crossing is a nine-night Awasi journey through Chile and Argentina, connecting the Atacama Desert, Patagonia and Mendoza with an overnight stay in Santiago. The route follows the Andes through three dramatically different landscapes.